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RETINOBLASTOMA-BINDING PROTEIN 4
Descriptors Found:
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DeCS
Descriptor
English
:
Retinoblastoma-Binding Protein 4
Descriptor
Spanish
:
Proteína 4 de Unión a Retinoblastoma
Descriptor
Portuguese
:
Proteína 4 de Ligação ao Retinoblastoma
Tree Number:
D05.500.781.750.500
D08.811.277.087.520.500.775
D08.811.277.087.520.750.775
D08.811.600.620.775
D08.811.600.795.775
D12.644.360.024.328.600
D12.776.157.057.158.600
D12.776.476.024.414.600
D12.776.580.219.200.500
D12.776.660.235.600.200.500
D12.776.660.769.600
D12.776.664.235.800.200.500
D12.776.930.700.890.200.500
Definition
English
:
A retinoblastoma-binding protein that is involved in
CHROMATIN
REMODELING
, histone deacetylation, and repression of GENETIC TRANSCRIPTION. Although initially discovered as a
retinoblastoma
binding protein it has an affinity for core
HISTONES
and is a subunit of
chromatin assembly factor-1
and
polycomb repressive complex 2.
History Note
English
:
2010
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53592
Unique Identifier:
D056505
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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